Invention Grant
- Patent Title: Pyrrolidine derivatives as angiotensin II type 2 antagonists
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Application No.: US15542071Application Date: 2016-01-12
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Publication No.: US10065943B2Publication Date: 2018-09-04
- Inventor: Jane Brown , Thomas David McCarthy , Alan Naylor , John Paul Watts
- Applicant: NOVARTIS AG
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Laura K. Madden
- Priority: AU2015900077 20150113; AU2015902922 20150723
- International Application: PCT/IB2016/050122 WO 20160112
- International Announcement: WO2016/113668 WO 20160721
- Main IPC: C07D403/04
- IPC: C07D403/04 ; C07D413/04 ; C07D495/04 ; C07D471/04 ; C07D401/04 ; C07D417/04
Abstract:
The invention relates to heterocyclic angiotensin II type 2 (AT2) receptor antagonists of formula (I), and pharmaceutically acceptable salts thereof, ((I) in which all of the variables are as defined in the specification, pharmaceutical compositions thereof, combinations thereof, and their use as medicaments, particularly for the treatment of neuropathic or inflammatory pain.
Public/Granted literature
- US20170369473A1 PYRROLIDINE DERIVATIVES AS ANGIOTENSIN II TYPE 2 ANTAGONISTS Public/Granted day:2017-12-28
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