Invention Grant
- Patent Title: Small molecule transcription modulators of bromodomains
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Application No.: US15314959Application Date: 2015-05-29
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Publication No.: US10065951B2Publication Date: 2018-09-04
- Inventor: Ming-MIng Zhou , Guillermo Gerona-Navarro , Yoel Rodriguez-Fernandez , Patrizia Casaccia
- Applicant: Icahn School of Medicine at Mount Sinai
- Applicant Address: US NY New York
- Assignee: Icahn School of Medicine at Mount Sinai
- Current Assignee: Icahn School of Medicine at Mount Sinai
- Current Assignee Address: US NY New York
- Agency: Fish & Richardson P.C.
- International Application: PCT/US2015/033178 WO 20150529
- International Announcement: WO2015/184257 WO 20151203
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61K31/437 ; A61K45/06 ; C12N5/079 ; C12N5/071
Abstract:
This disclosure relates generally to compounds and compositions comprising one or more indole analogs. These compounds are useful for treating diseases associated with NF-kB and p53 activity, such as cancer and inflammatory diseases.
Public/Granted literature
- US20170107218A1 Small Molecule Transcription Modulators of Bromodomains Public/Granted day:2017-04-20
Information query
