Invention Grant
- Patent Title: Substituted imidazo[4,5-c]pyridines as SSAO inhibitors
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Application No.: US15506885Application Date: 2015-09-17
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Publication No.: US10065954B2Publication Date: 2018-09-04
- Inventor: Max Espensen , Lee Patient , Edward Savory
- Applicant: Proximagen Limited
- Applicant Address: GB Cambridge
- Assignee: PROXIMAGEN LIMITED
- Current Assignee: PROXIMAGEN LIMITED
- Current Assignee Address: GB Cambridge
- Agency: Greenblum & Bernstein, P.L.C.
- Priority: GB1416446.1 20140917
- International Application: PCT/GB2015/052690 WO 20150917
- International Announcement: WO2016/042331 WO 20160324
- Main IPC: A61K31/437
- IPC: A61K31/437 ; C07D471/04
![Substituted imidazo[4,5-c]pyridines as SSAO inhibitors](/abs-image/US/2018/09/04/US10065954B2/abs.jpg.150x150.jpg)
Abstract:
Specific compounds of formula (Ia): and pharmaceutically acceptable salts thereof. Pharmaceutical compositions of the specific compounds of formula (Ia) and pharmaceutically acceptable salts thereof. A method for inhibiting tumor growth in a subject that includes administering to the subject an effective amount of a compound selected from the specific compounds of formula (Ia) and pharmaceutically acceptable salts thereof. A method for modulating semicarbazide-sensitive amine oxidase activity in a subject that includes administering to the subject an effective amount of a compound selected from the specific compounds of formula (Ia) and pharmaceutically acceptable salts thereof.
Public/Granted literature
- US20170362218A1 IMIDAZO[4,5-C]PYRIDINE DERIVED SSAO INHIBITORS Public/Granted day:2017-12-21
Information query
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