Invention Grant
- Patent Title: Crystalline forms of a bruton's tyrosine kinase inhibitor
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Application No.: US15901118Application Date: 2018-02-21
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Publication No.: US10065968B2Publication Date: 2018-09-04
- Inventor: Norbert Purro , Mark S. Smyth , Erick Goldman , David D. Wirth
- Applicant: Pharmacyclics LLC
- Applicant Address: US CA Sunnyvale
- Assignee: Pharmacyclics LLC
- Current Assignee: Pharmacyclics LLC
- Current Assignee Address: US CA Sunnyvale
- Agency: Foley Hoag LLP
- Main IPC: C07D487/04
- IPC: C07D487/04 ; C07D295/023

Abstract:
Described herein is the Bruton's tyrosine kinase (Btk) inhibitor 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, including crystalline forms, solvates and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions that include the Btk inhibitor, as well as methods of using the Btk inhibitor, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.
Public/Granted literature
- US20180179215A1 CRYSTALLINE FORMS OF A BRUTON'S TYROSINE KINASE INHIBITOR Public/Granted day:2018-06-28
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