Invention Grant
- Patent Title: Compositions and methods for inhibiting arginase activity
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Application No.: US15337041Application Date: 2016-10-28
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Publication No.: US10065974B2Publication Date: 2018-09-04
- Inventor: Eric B. Sjogren , Jim Li , Michael Van Zandt , Darren Whitehouse
- Applicant: Calithera Biosciences, Inc.
- Agency: Dechert LLP
- Agent Carl A. Morales; Seth E. Snyder
- Main IPC: C07F5/02
- IPC: C07F5/02 ; C07K16/28 ; A61K31/69 ; A61K39/395 ; A61K45/06 ; A61K39/00

Abstract:
The invention relates to a novel class of compounds that exhibit activity inhibitory activity toward arginase, and pharmaceutical compositions comprising the compounds of the invention. Also provided herein are methods of treating cancer with the arginase inhibitors of the invention.
Public/Granted literature
- US20170121352A1 COMPOSITIONS AND METHODS FOR INHIBITING ARGINASE ACTIVITY Public/Granted day:2017-05-04
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