Invention Grant
- Patent Title: Methods of diagnosing diseases caused by or associated with neurofibrillary tangles by phosphospecific antibodies recognising Tau
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Application No.: US15337964Application Date: 2016-10-28
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Publication No.: US10066010B2Publication Date: 2018-09-04
- Inventor: Andrea Pfeifer , Andreas Muhs , Maria Pihlgren , Oskar Adolfsson , Fred Van Leuven
- Applicant: AC IMMUNE S.A. , KATHOLIEKE UNIVERSITEIT LEUVEN
- Applicant Address: CH Lausanne BE Leuven
- Assignee: AC IMMUNE S.A.,KATHOLIEKE UNIVERSITEIT LEUVEN
- Current Assignee: AC IMMUNE S.A.,KATHOLIEKE UNIVERSITEIT LEUVEN
- Current Assignee Address: CH Lausanne BE Leuven
- Agency: McNeill Baur PLLC
- Priority: EP12163319 20120405
- Main IPC: A61K49/00
- IPC: A61K49/00 ; A61K39/395 ; A61K39/00 ; C12P21/08 ; G01N33/53 ; C07K16/18 ; G01N33/68
Abstract:
The present invention relates to methods and compositions for the therapeutic and diagnostic use in the treatment of diseases and disorders which are caused by or associated with neurofibrillary tangles. In particular, the invention relates to antibodies, which specifically recognize and bind to phosphorylated pathological protein tau-conformers and to methods and compositions involving said antibodies for the therapeutic and diagnostic use in the treatment of tauopathies including Alzheimer's Disease (AD).
Public/Granted literature
- US20170137502A1 PHOSPHOSPECIFIC ANTIBODIES RECOGNISING TAU Public/Granted day:2017-05-18
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