Invention Grant
- Patent Title: ω-functionalized polymers, junction-functionalized block copolymers, polymer bioconjugates, and radical chain extension polymerization
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Application No.: US15428063Application Date: 2017-02-08
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Publication No.: US10066043B2Publication Date: 2018-09-04
- Inventor: Patrick S. Stayton , Allan S. Hoffman , Anthony J. Convertine , Scott M. Henry , Robert W. Overell , Paul H. Johnson
- Applicant: University of Washington , PhaseRx, Inc.
- Applicant Address: US WA Seattle US WA Seattle
- Assignee: University of Washington,PhaseRx, Inc.
- Current Assignee: University of Washington,PhaseRx, Inc.
- Current Assignee Address: US WA Seattle US WA Seattle
- Agency: Christensen O'Connor Johnson Kindness PLLC
- Main IPC: A61K31/74
- IPC: A61K31/74 ; C08F293/00 ; A61K49/00 ; A61K47/48
Abstract:
Polymeric compounds having spatially controlled bioconjugation sites are described. Functionalization is achieved by selective ω-terminal chain extension of polymer chains by radical polymerization, such as reversible addition-fragmentation chain transfer (RAFT) polymerization.
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