- Patent Title: Kit and method for promoting mesenchymal stem cell differentiation
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Application No.: US14700173Application Date: 2015-04-30
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Publication No.: US10066208B2Publication Date: 2018-09-04
- Inventor: Feng-Huei Lin , Jui-Sheng Sun , Chunching Li , Ching-Yun Chen , Cherng-Jyh Ke
- Applicant: NATIONAL TAIWAN UNIVERSITY
- Applicant Address: TW Taipei
- Assignee: NATIONAL TAIWAN UNIVERSITY
- Current Assignee: NATIONAL TAIWAN UNIVERSITY
- Current Assignee Address: TW Taipei
- Agent Hannah M. Tien
- Priority: TW103140322A 20141120
- Main IPC: C12N5/077
- IPC: C12N5/077 ; C12N5/0775
Abstract:
The present invention is related to a kit comprising: (a) a mesenchymal stem cell; (b) a gelatin-hyaluronan-chondroitin tri-copolymer scaffold; (c) a kartogenin; and (d) a bioreactor. The present invention is also related to a method for promoting differentiation of a mesenchymal stem cell into cartilage tissue, comprising: (a) culturing the mesenchymal stem cell on a gelatin- hyaluronan-chondroitin tri-copolymer scaffold in the presence of a kartogenin; and (b) culturing the mesenchymal stem cell and the gelatin-hyaluronan-chondroitin tri-copolymer scaffold in a bioreactor.
Public/Granted literature
- US20160145574A1 KIT AND METHOD FOR PROMOTING MESENCHYMAL STEM CELL DIFFERENTIATION Public/Granted day:2016-05-26
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