Invention Grant
- Patent Title: Treatment using truncated Trk B and Trk C antagonists
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Application No.: US15222710Application Date: 2016-07-28
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Publication No.: US10066229B2Publication Date: 2018-09-04
- Inventor: Horacio Uri Saragovi , Fabrice Piu
- Applicant: Otonomy, Inc. , Horacio Uri Saragovi
- Applicant Address: US CA San Diego
- Assignee: OTONOMY, INC.
- Current Assignee: OTONOMY, INC.
- Current Assignee Address: US CA San Diego
- Agency: Wilson, Sonsini, Goodrich & Rosati
- Main IPC: A61K31/70
- IPC: A61K31/70 ; C07H21/02 ; C07H21/04 ; C12N15/113 ; A61K31/7088 ; C12N15/86 ; C12N7/00 ; A61K9/00 ; A61K9/06 ; A61K48/00 ; C12N5/00

Abstract:
Disclosed herein are methods, compositions, vectors, and kits comprising an antagonist of a truncated TrkC or a truncated TrkB. Also described herein are methods of treating and/or preventing an otic disease or condition associated with an elevated expression level of a truncated TrkC or truncated TrkB isoform.
Public/Granted literature
- US20170029822A1 TREATMENT USING TRUNCATED TRK B AND TRK C ANTAGONISTS Public/Granted day:2017-02-02
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