The invention relates to a method for operating an internal combustion engine comprising at least one turbocharger, at least one catalytic converter and a variable valve train, a valve overlap parameter being determined in at least one operating mode of the internal combustion engine and being used to set the valve train. According to the invention, the valve overlap parameter is adapted on the basis of at least one parameter for the condition of the catalytic converter and/or at least one parameter for the condition of the turbocharger, prior to being used to set the valve train. The invention also relates to an internal combustion engine.