A differential pressure measuring pickup comprises a measuring pickup body and a differential pressure sensor. The measuring pickup body has a process interfacing surface with a first pressure input opening and a second pressure input opening. The differential pressure sensor can be loaded with a first pressure through the first pressure input opening and with a second pressure through the second pressure input opening. The first pressure input opening is closed by way of a first separating diaphragm and the second pressure input opening is closed by way of a second separating diaphragm. The first separating diaphragm is sealed with respect to the surroundings by way of a first seal, and wherein the second separating diaphragm is sealed with respect to the surroundings by way of a second seal. The differential pressure measuring pickup is tensioned during measuring operation with the process interfacing surface thereof against a process interfacing flange, wherein at least one plate-shaped spacer element with plane-parallel surfaces is clamped in between the process interfacing flange and the process interfacing surface, which spacer element defines the spacing between the process interfacing surface and the process interfacing flange and limits clamping of the seals between the process interfacing surface and the process interfacing flange.