Invention Grant
- Patent Title: Compounds and methods for PEG metabolite and PEG breakdown product assays
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Application No.: US15057989Application Date: 2016-03-01
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Publication No.: US10067103B2Publication Date: 2018-09-04
- Inventor: Kevin Douglass , David Humphries , Beauregard Mason , Mario Pellerin
- Applicant: ColonaryConcepts LLC
- Applicant Address: US MA Newton
- Assignee: COLONARYCONCEPTS LLC
- Current Assignee: COLONARYCONCEPTS LLC
- Current Assignee Address: US MA Newton
- Agency: Wilson Sonsini Goodrich & Rosati
- Main IPC: G01N30/72
- IPC: G01N30/72 ; G01N30/06 ; C07C69/78 ; G01N33/50 ; C07C69/76
Abstract:
Disclosed herein are compounds and methods for identifying and quantifying a metabolite or breakdown product of PEG. A sample may be assayed for PEG metabolites or breakdown products using liquid chromatography combined with mass spectrometry. Derivatization of the PEG metabolites or breakdown products within the sample with pentaflurobenzoyl chloride in conjunction with negative chemical ionization mode liquid chromatography optimizes the assay.
Public/Granted literature
- US20160258912A1 COMPOUNDS AND METHODS FOR PEG METABOLITE AND PEG BREAKDOWN PRODUCT ASSAYS Public/Granted day:2016-09-08
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