Methods and apparatus for identifying potentially seizure-inducing virtual reality content are disclosed herein. An example apparatus includes a virtual reality presentation device to display virtual reality content for exposure to a user and a neurological data collector to access first neurological response data collected from the user during exposure to the virtual reality content. The example apparatus includes a predictor to generate a prediction on a likelihood that a portion of the virtual reality content will trigger a seizure based on a first vector characterizing the portion and the first neurological response data. The example apparatus includes a content modifier to modify the portion of the virtual reality content into modified virtual reality content in response to the prediction. The content modifier is to transmit the modified virtual reality content to the virtual reality presentation device.