An electronic device and a single-layer mutual-capacitance touch screen are provided. The touch screen includes multiple sensing electrode groups disposed in a first direction in parallel, multiple bonding pads, multiple first lead wires and multiple second lead wires. The sensing electrode group includes a first unit including multiple first electrodes and a second unit including multiple electrode pairs. The electrode pair includes a second electrode at a first side of the first unit and a third electrode at a second side of the first unit. The first lead wires and the second lead wires connect the first electrodes and the electrode pairs with corresponding bonding pads respectively. In any two adjacent electrode pairs, adjacent ends of both two second electrodes and two third electrodes are opposite to the first electrode in the first direction.