A method of monitoring memory performance comprises selecting a first portion of memory from two or more portions of memory in accordance with an adaptive mode indicated by configuration bits in a control register; monitoring memory accesses to the selected portion of memory during a first sampling period; selecting a different portion of memory from the two or more portions of memory in accordance with the adaptive mode for monitoring the different portion of memory in a subsequent sampling period; monitoring memory accesses to the different portion of memory during the subsequent sampling period; recording a respective number of memory accesses for each portion of memory over a plurality of sampling periods; and generating one or more interrupts to output data regarding the monitored memory accesses for data analysis.