A method, apparatus and computer program product provide mechanisms for implementing a clinical client monitoring and configuration system. The method includes receiving system data from a plurality of client clinical devices, each of the plurality of client clinical devices implementing a reporting framework for transmission of the system data, determining, based on the system data, at least one clinical client application configuration change for a clinical application executing on at least one of the plurality of client clinical devices or another client clinical device other than the plurality of client clinical devices, and transmitting instructions to the clinical application for implementation of the at least one clinical client application configuration change.