Devices and methods for multiplexed imaging are provided. In one embodiment, an imaging device can simultaneously direct light of a same spectrum from each of a plurality of image channels onto an image sensor to create a multiplexed image on the sensor. Each image channel can collect light from different portions of an extended field of view or from the same portion with different perspectives. The device can also include one or more encoders to encode light from the channels prior to detection. The devices and methods described herein can also include disambiguating a captured multiplexed image to create images for each of the plurality of image channels. Disambiguated images can cover the extended field of view at a high spatial resolution despite using only a single small format image sensor, or can produce stereo or 3D images having the full resolution of the sensor.