Systems and methods are disclosed herein to provide infrared imaging systems with improved electronics architectures. In one embodiment, an infrared imaging system is provided that includes an infrared imaging sensor for capturing infrared image data and a main electronics block for efficiently processing the captured infrared image data. The main electronics block may include a plurality of vector processors each configured to operate on multiple pixels of the infrared image data in parallel to efficiently exploit pixel-level parallelism. Each vector processor may be communicatively coupled to a local memory that provides high bandwidth, low latency access to a portion of the infrared image data for the vector processor to operate on. The main electronics block may also include a general-purpose processor configured to manage data flow to/from the local memories and other system functionalities. The main electronics block may be implemented as a system-on-a-chip.