Invention Grant
- Patent Title: Transgenic transchromosomal rodents for making human antibodies
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Application No.: US15218202Application Date: 2016-07-25
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Publication No.: US10076103B2Publication Date: 2018-09-18
- Inventor: Kazuma Tomizuka , Isao Ishida , Nils Lonberg , Edward L. Halk
- Applicant: KYOWA HAKKO KIRIN CO., LTD. , E. R. SQUIBB & SONS, L.L.C.
- Applicant Address: JP Tokyo US NJ Princeton
- Assignee: KYOWA HAKKO KIRIN CO., LTD.,E.R. SQUIBB & SONS, L.L.C.
- Current Assignee: KYOWA HAKKO KIRIN CO., LTD.,E.R. SQUIBB & SONS, L.L.C.
- Current Assignee Address: JP Tokyo US NJ Princeton
- Agency: Baker Botts L.L.P.
- Main IPC: C07H21/04
- IPC: C07H21/04 ; A01K67/027 ; C07K14/735 ; C07K16/00 ; C07K16/18 ; C07K16/24 ; C07K16/28 ; C12N15/85 ; A01K67/02 ; C12N5/0781 ; C12N5/16 ; C12P21/00 ; C12Q1/6881 ; A61K39/00
Abstract:
The present invention provides novel transgenic nonhuman mammals capable of producing human sequence antibodies, as well as methods of producing and using these antibodies.
Public/Granted literature
- US20160324131A1 TRANSGENIC TRANSCHROMOSOMAL RODENTS FOR MAKING HUMAN ANTIBODIES Public/Granted day:2016-11-10
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