A Variable Angle Surgical Instrument is disclosed and generally comprises: a rail portion including a proximal end, a distal end, and a longitudinal axis extending therebetween; a jaw portion operably coupled to the distal end of the rail portion; wherein the jaw portion rotates to variable angles relative to the longitudinal axis, and the jaw portion operates between a closed position and an open position to clamp down and remove tissue; a locking mechanism operably coupled to the rail portion to lock the jaw portion to an angled position.