Invention Grant
- Patent Title: Tetrahydro-benzoimidazolyl modulators of TGR5
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Application No.: US15303746Application Date: 2015-04-14
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Publication No.: US10077241B2Publication Date: 2018-09-18
- Inventor: Xuqing Zhang , Mark J. Wall , Zhihua Sui
- Applicant: Janssen Pharmaceutica NV
- Applicant Address: BE Beerse
- Assignee: Jansen Pharmaceutica NV
- Current Assignee: Jansen Pharmaceutica NV
- Current Assignee Address: BE Beerse
- International Application: PCT/US2015/025702 WO 20150414
- International Announcement: WO2015/160772 WO 20151022
- Main IPC: C07D405/04
- IPC: C07D405/04 ; C07D413/04 ; C07D235/02 ; C07D403/12 ; A61K31/12 ; A61K31/4184 ; A61K31/4188 ; A61K31/423 ; A61K31/427 ; A61K31/5377 ; C07D407/12 ; C07D409/12 ; C07D413/12 ; C07D417/12 ; C07D491/052 ; A61K45/06 ; C07D401/12
Abstract:
The present invention comprises compounds of Formula (I). wherein: R1, R2, R3, R4, R5, R6, R7, R8, X, Z1 and Z2 are defined in the specification.
Public/Granted literature
- US20170029381A1 TETRAHYDRO-BENZOIMIDAZOLYL MODULATORS OF TGR5 Public/Granted day:2017-02-02
Information query
