Invention Grant
- Patent Title: Bicyclic heterocyclic derivatives as bromodomain inhibitors
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Application No.: US15110361Application Date: 2015-01-06
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Publication No.: US10077259B2Publication Date: 2018-09-18
- Inventor: Susanta Samajdar , Chandrasekhar Abbineni , Sanjita Sasmal , Subramanya Hosahalli
- Applicant: Orion Corporation
- Applicant Address: FI Espoo
- Assignee: Orion Corporation
- Current Assignee: Orion Corporation
- Current Assignee Address: FI Espoo
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- Priority: IN125/CHE/2014 20140109
- International Application: PCT/IB2015/050090 WO 20150106
- International Announcement: WO2015/104653 WO 20150716
- Main IPC: A61K31/4709
- IPC: A61K31/4709 ; A61K31/497 ; A61K31/506 ; C07D401/04 ; C07D401/12 ; C07D401/14 ; C07D413/04 ; C07D413/14 ; C07D417/12

Abstract:
The present disclosure provides bicyclic heterocyclic derivatives of formula (I), which may be therapeutically useful, more particularly as bromodomain inhibitors; (I), in which R1, R2, R3, R4, L1, L2, Cy1, Cy2, X, n, and dotted line have the same meaning given in the specification, and pharmaceutically acceptable salts or pharmaceutically acceptable stereoisomers thereof that are useful in the treatment and prevention of diseases or disorders, in particular their use in diseases or disorders associated as bromodomain inhibitors. The present disclosure also provides preparation of compounds and pharmaceutical formulations comprising at least one of bicyclic heterocyclic derivatives of formula (I), together with a pharmaceutically acceptable carrier, diluent, or excipient.
Public/Granted literature
- US20160368906A1 BICYCLIC HETEROCYCLIC DERIVATIVES AS BROMODOMAIN INHIBITORS Public/Granted day:2016-12-22
Information query
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