Invention Grant
- Patent Title: Esophageal cancer marker and use thereof
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Application No.: US15108251Application Date: 2014-12-25
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Publication No.: US10077316B2Publication Date: 2018-09-18
- Inventor: Tetsuji Naka , Satoshi Serada , Minoru Fujimoto , Masayoshi Toyoura , Yuji Shoya
- Applicant: National University Corporation Kochi University
- Applicant Address: JP Kochi
- Assignee: National University Corporation, Kochi University
- Current Assignee: National University Corporation, Kochi University
- Current Assignee Address: JP Kochi
- Agency: Seed IP Law Group LLP
- Priority: JP2013-272085 20131227
- International Application: PCT/JP2014/006455 WO 20141225
- International Announcement: WO2015/098112 WO 20150702
- Main IPC: C07K16/30
- IPC: C07K16/30 ; A61K31/713 ; G01N33/574 ; C12Q1/6886 ; C07K16/28 ; C12N15/113 ; A61K39/00
Abstract:
The present invention relates to an esophageal cancer marker and application thereof. The present invention relates to: a marker that includes Glypican-1 or an expression product thereof, or a fragment or derivative thereof, and serves to identify esophageal cancer; a detection agent that includes a substance that binds to Glypican-1 or an expression product thereof; and a composition that includes a Glypican-1 inhibitor and serves to prevent or treat esophageal cancer. Herein, Glypican-1 can be SEQ ID NO: 1 (nucleic acid sequence) or SEQ ID NO: 2 (amino acid sequence), or an equivalent thereof.
Public/Granted literature
- US20170066836A1 ESOPHAGEAL CANCER MARKER AND USE THEREOF Public/Granted day:2017-03-09
Information query
