Invention Grant
- Patent Title: Coryneform bacterium and method for producing heterologous fusion proteins
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Application No.: US14924201Application Date: 2015-10-27
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Publication No.: US10077447B2Publication Date: 2018-09-18
- Inventor: Sergey Vasilievich Smirnov , Veronika Aleksandrovna Kotliarova , Hidemi Fujii , Masakazu Sugiyama
- Applicant: AJINOMOTO CO., INC.
- Applicant Address: JP Tokyo
- Assignee: AJINOMOTO CO., INC.
- Current Assignee: AJINOMOTO CO., INC.
- Current Assignee Address: JP Tokyo
- Agency: Cermak Nakajima & McGowan LLP
- Agent Shelly Guest Cermak
- Priority: RU2013119826 20130429
- Main IPC: C12N15/77
- IPC: C12N15/77 ; C07K14/605 ; C07K1/107 ; C07K16/32 ; C07K14/34 ; C12P21/02 ; C12P21/06 ; C12N15/62 ; C07K1/00
Abstract:
The present invention provides a coryneform bacterium having an ability to produce a heterologous fusion protein by secretory production, which has been modified to express a genetic construct for secretory production of the heterologous fusion protein encoding at least a heterologous fusion protein comprising an extein and an intein having an activity of acyl rearrangement. The method for producing proteins modified at the C-terminus is also provided.
Public/Granted literature
- US20160060640A1 Coryneform Bacterium and Method for Producing Heterologous Fusion Proteins Public/Granted day:2016-03-03
Information query
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