Invention Grant
- Patent Title: Microbiological process
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Application No.: US15118924Application Date: 2015-02-17
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Publication No.: US10077458B2Publication Date: 2018-09-18
- Inventor: Emilio Alvarez-Ruiz , Andrew John Collis , Alison Sarah Dann , Andrew Peter Fosberry , Sarah Jane Ready , Maria Jesus Vazquez Muniz
- Applicant: GlaxoSmithKline Intellectual Property Development Limited
- Applicant Address: GB Brentford, Middlesex
- Assignee: GlaxoSmithKline Intellectual Property Development Limited
- Current Assignee: GlaxoSmithKline Intellectual Property Development Limited
- Current Assignee Address: GB Brentford, Middlesex
- Agent Elizabeth J. Hecht; Edward R. Gimmi
- Priority: EP14382054 20140217
- International Application: PCT/EP2015/053282 WO 20150217
- International Announcement: WO2015/121488 WO 20150820
- Main IPC: A61K31/445
- IPC: A61K31/445 ; C12P17/12 ; C12R1/465 ; C12P19/26 ; C07D211/46 ; C12N1/20

Abstract:
A process for the microbial synthesis of migalastat, specifically a process for the production of migalastat comprising culturing a microorganism under conditions such that at least one imino sugar is produced and detecting and/or isolating an imino sugar produced by said microorganism, and the microorganisms used in this process. The invention also comprises migalastat produced according to the above method and pharmaceutical compositions and uses thereof.
Public/Granted literature
- US20160355856A1 MICROBIOLOGICAL PROCESS Public/Granted day:2016-12-08
Information query
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