Invention Grant
- Patent Title: Process and molecular biomarker
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Application No.: US15326972Application Date: 2015-07-13
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Publication No.: US10077476B2Publication Date: 2018-09-18
- Inventor: Rommel Mario Rodriguez Burbano , Thais Brilhante Pontes , Leticia Martins Lamarao , Caroline De Fatima Aquino Moreira Nunes
- Applicant: UNIVERSIDADE FEDERAL DO PARA—UFPA , CENTRO DE HEMOTERAPIA E HEMATOLOGIA DO PARA—HEMOPA
- Applicant Address: BR BR
- Assignee: UNIVERSIDADE FEDERAL DO PARA-UFPA,CENTRO DE HEMOTERAPIA E HEMATOLOGIA DO PARA—HEMOPA
- Current Assignee: UNIVERSIDADE FEDERAL DO PARA-UFPA,CENTRO DE HEMOTERAPIA E HEMATOLOGIA DO PARA—HEMOPA
- Current Assignee Address: BR BR
- Agency: Hayes Soloway P.C.
- Priority: BR102014021701 20140714
- International Application: PCT/BR2015/050090 WO 20150713
- International Announcement: WO2016/008020 WO 20160121
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12Q1/6883

Abstract:
A process and molecular biomarker for platelets stored in blood banks provides for efficient verification of which platelet concentrate bags are in good condition for transfusion by measuring, by real-time polymerase chain reaction, expression levels of hsa-miR-127 and hsa-miR-320a microRNAs as the first process and biomarker predictor of platelet's cell aging during storage and the consequent presence of storage lesions as a quality test of these bags.
Public/Granted literature
- US20170204464A1 PROCESS AND MOLECULAR BIOMARKER Public/Granted day:2017-07-20
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