To prevent nuisance marine growth in a valve, particularly a ball valve, used to regulate a flow of seawater, a compound for lubricating and preventing nuisance marine growth is provided in the valve. The nuisance marine growth preventing compound includes a substantially uniform mixture of marine grease and an antifouling agent. The compound is introduced into the valve such that the compound is provided between and contacts a valve body and a ball that regulates the flow of seawater within the valve, and inhibits nuisance marine growth at a space between the ball and the valve body which is occupied by the compound.