During an analysis technique, a three-dimensional (3D) image of a portion of an individual is transformed to facilitate accurate determination of detailed annotation of an anatomical structure (such as: specifying the size of the anatomical structure based on annotation markers, an orientation of the anatomical structure, a direction of the anatomical structure and/or a location of the anatomical structure). In particular, in response to receiving information specifying a two-dimensional (2D) plane having an angular position in the 3D image, the 3D image is translated and rotated from an initial position and orientation so that the 2D plane is presented in an orientation parallel to a reference 2D plane of a display. Then, after information specifying the detailed annotation in the 2D plane is received, the 3D image is translated and rotated back to the initial position and orientation.