Examples of front-end modules, apparatuses and methods for coupling compensation in a closed-loop digital pre-distortion (DPD) system are described. The closed-loop DPD circuit may include a PA and a loopback path. The PA may receive a PA input signal and amplify the PA input signal to provide a PA output signal proportional to a product of the PA input signal and a gain of the PA. The loopback path may receive the PA output signal to output a loopback signal. A forward coupling and a backward coupling may exist between the PA input signal and an output of the loopback path. The output of the loopback path may be proportional to a product of the PA output signal and a gain of the loopback path. The loopback path may include a coupling cancellation mechanism configured to cancel couplings between the PA input signal and the loopback signal.