Invention Grant
- Patent Title: Formulation inhibiting effects of low acid environment
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Application No.: US15532721Application Date: 2015-12-01
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Publication No.: US10085991B2Publication Date: 2018-10-02
- Inventor: Lei Zhu , Yvonne Cegielnik , Qun Lu
- Applicant: Merck Sharp & Dohme Corp. , Lei Zhu , Yvonne Cegielnik , Qun Lu
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent H. Eric Fischer; John C. Todaro
- International Application: PCT/US2015/063060 WO 20151201
- International Announcement: WO2016/089796 WO 20160609
- Main IPC: A61K31/52
- IPC: A61K31/52 ; A61K9/00 ; A61K47/26 ; A61K47/02 ; A61K47/20 ; A61K47/12 ; A61K47/32 ; A61K9/10 ; A61K47/38
Abstract:
The present invention is directed to formulations comprising PVP polymer, a dispersion of a compound of Formula I (API), and citric acid, which formulations mitigate the effects of coadministering the compound of Formula I with a proton pump inhibitor compound.
Public/Granted literature
- US20170354658A1 FORMULATION INHIBITING EFFECTS OF LOW ACID ENVIRONMENT Public/Granted day:2017-12-14
Information query
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