Invention Grant
- Patent Title: Compounds and their methods of use
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Application No.: US14646634Application Date: 2013-11-21
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Publication No.: US10087172B2Publication Date: 2018-10-02
- Inventor: Rene M. Lemieux , Janeta Popovici-Muller , Francesco G. Salituro , Jeffrey O. Saunders , Jeremy Travins , Yongsheng Chen
- Applicant: AGIOS PHARMACEUTICALS, INC
- Applicant Address: US MA Cambridge
- Assignee: AGIOS PHARMACEUTICALS, INC.
- Current Assignee: AGIOS PHARMACEUTICALS, INC.
- Current Assignee Address: US MA Cambridge
- Agency: Goodwin Procter LLP
- Priority: WOPCT/CN2012/085023 20121122; WOPCT/CN2013/000294 20130315
- International Application: PCT/CN2013/001428 WO 20131121
- International Announcement: WO2014/079150 WO 20140530
- Main IPC: C07D417/08
- IPC: C07D417/08 ; C07D417/14 ; C07D285/135

Abstract:
Provided are compounds of formula (I), which can inhibit glutaminase. Pharmaceutical compositions comprising these compounds and uses as glutaminase inhibitors for treating cancers thereof are also provided.
Public/Granted literature
- US20150291576A1 COMPOUNDS AND THEIR METHODS OF USE Public/Granted day:2015-10-15
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