Invention Grant
- Patent Title: Selectively substituted quinoline compounds
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Application No.: US15670904Application Date: 2017-08-07
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Publication No.: US10087174B2Publication Date: 2018-10-02
- Inventor: J. Eric Carlson , Lynn Hawkins , Sally Ishizaka , Shawn Schiller , Chikako Ogawa , Atsushi Endo
- Applicant: EISAI R&D MANAGEMENT CO., LTD.
- Applicant Address: JP Tokyo
- Assignee: EISAI R&D MANAGEMENT CO., LTD.
- Current Assignee: EISAI R&D MANAGEMENT CO., LTD.
- Current Assignee Address: JP Tokyo
- Agency: Buchanan Ingersoll & Rooney PC
- Main IPC: C07D413/14
- IPC: C07D413/14 ; C07D417/14 ; C07D413/04 ; C07D215/48 ; C07D471/04 ; C07D487/10 ; C07D471/10 ; C07D401/14 ; C07D401/10 ; C07D403/14 ; C07D451/04 ; C07D487/04 ; C07D493/10 ; C12Q1/6897 ; G01N33/50
Abstract:
Embodiments of the disclosure relate to selectively substituted quinoline compounds that act as antagonists or inhibitors for Toll-like receptors 7 and/or 8, and their use in pharmaceutical compositions effective for treatment of systemic lupus erythematosus (SLE) and lupus nephritis.
Public/Granted literature
- US20180030045A1 SELECTIVELY SUBSTITUTED QUINOLINE COMPOUNDS Public/Granted day:2018-02-01
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