Invention Grant
- Patent Title: Benzamide imidazopyrazine Btk inhibitors
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Application No.: US15538902Application Date: 2015-12-17
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Publication No.: US10087188B2Publication Date: 2018-10-02
- Inventor: Jian Liu , Joseph A. Kozlowski , Abdul-Basit Alhassan , Sobhana Babu Boga , Xiaolei Gao , Deodial Guy Guiadeen , Jyhshing Wang , Wensheng Yu , Jiaqiang Cai , Shilan Liu , Dahai Wang , Hao Wu , Chundao Yang
- Applicant: MERCK SHARP & DOHME CORP.
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Matthew A. Leff; Laura M. Ginkel
- Priority: WOPCT/CN2014/095763 20141231
- International Application: PCT/US2015/066238 WO 20151217
- International Announcement: WO2016/109223 WO 20160707
- Main IPC: C07D487/04
- IPC: C07D487/04 ; C07D519/00 ; A61K31/4985 ; A61K31/5377
Abstract:
The present invention provides Bruton's Tyrosine Kinase (Btk) inhibitor compounds according to Formula (I), or pharmaceutically acceptable salts thereof, or to pharmaceutical compositions comprising these compounds and to their use in therapy. In particular, the present invention relates to the use of Btk inhibitor compounds of Formula (I) in the treatment of Btk mediated disorders.
Public/Granted literature
- US20170362242A1 BENZAMIDE IMIDAZOPYRAZINE BTK INHIBITORS Public/Granted day:2017-12-21
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