Invention Grant
- Patent Title: Human ULIP/CRMP protein and use thereof in diagnosis and treatment of cancers and paraneoplastic neurological syndromes
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Application No.: US13741876Application Date: 2013-01-15
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Publication No.: US10087220B2Publication Date: 2018-10-02
- Inventor: Michele Aguera , Jean-Christophe Antoine , Marie-Francoise Belin , Jerome Honnorat , Veronique Rogemond
- Applicant: INSTITUT NATIONAL DE LA SANTA ET DE LA RECHERCHE MEDICALE (INSERM)
- Applicant Address: FR Paris
- Assignee: INSTITUT NATIONAL DE LA SANTA ET DE LA RECHERCHE MEDICALE (INSERM)
- Current Assignee: INSTITUT NATIONAL DE LA SANTA ET DE LA RECHERCHE MEDICALE (INSERM)
- Current Assignee Address: FR Paris
- Agency: Stites & Harbison, PLLC
- Agent B. Aaron Schulman, Esq.
- Priority: FR0002566 20000229; FR0005005 20000418
- Main IPC: C07K14/705
- IPC: C07K14/705 ; C07K14/47 ; C07K14/435 ; C07K16/18 ; G01N33/68 ; A61K38/00
Abstract:
A purified polypeptide, designated ULIP6, comprising the amino acid sequence SEQ ID No. 2 or an epitopic fragment of said polypeptide, comprising the sequence SEQ ID No. 4, is provided along with its nucleic acid sequences. In addition, antibodies to the polypeptide and methods of diagnosing paraneoplastic neurological syndromes and/or for the early diagnosis of the formation of cancerous tumors are also provided.
Public/Granted literature
Information query
