Invention Grant
- Patent Title: Glycoconjugates and use thereof as vaccine against Shigella flexneri serotype 3a and X
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Application No.: US14310667Application Date: 2014-06-20
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Publication No.: US10087242B2Publication Date: 2018-10-02
- Inventor: Laurence Mulard , Julien Boutet , Catherine Guerreiro , Farida Nato , Philippe Sansonetti , Armelle Phalipon
- Applicant: INSTITUT PASTEUR , Centre National De La Recherche Scientifique , Universite Paris Descartes
- Applicant Address: FR Paris FR Paris FR Paris
- Assignee: INSTITUT PASTEUR,CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE,UNIVERSITE PARIS DESCARTES
- Current Assignee: INSTITUT PASTEUR,CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE,UNIVERSITE PARIS DESCARTES
- Current Assignee Address: FR Paris FR Paris FR Paris
- Agency: Oblon, McClelland, Maier & Neustadt, L.L.P.
- Priority: CA2591253 20070605
- Main IPC: C07H5/04
- IPC: C07H5/04 ; C07H1/00 ; C07K16/12 ; C07H3/06 ; C07H3/04 ; A61K47/64
Abstract:
The present invention relates to compounds derived from sugars which reproduce the epitopes of Shigella flexneri serotypes 3a and X and to the use thereof for the preparation of vaccine compositions. More specifically, the subject matter of the present invention relates to novel glycoconjugated compounds comprising oligosaccharides or polysaccharides described hereinafter, to the method for synthesizing these oligosaccharides or polysaccharides and glycoconjugates, to derivatives of these oligosaccharides or polysaccharides, to compositions containing same, and also to the use of the glycoconjugates for vaccination purposes. Finally, the present invention relates to methods for diagnosing a Shigella flexneri infection using one or more oligosaccharides or polysaccharides or conjugates thereof.
Public/Granted literature
- US20150050282A1 GLYCOCONJUGATES AND USE THEREOF AS VACCINE AGAINST SHIGELLA FLEXNERI SEROTYPE 3a AND X Public/Granted day:2015-02-19
Information query
