Invention Grant
- Patent Title: Method for producing differentiated cells
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Application No.: US14925508Application Date: 2015-10-28
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Publication No.: US10087419B2Publication Date: 2018-10-02
- Inventor: Koji Eto , Naoya Takayama , Sou Nakamura , Hiromitsu Nakauchi
- Applicant: The University of Tokyo
- Applicant Address: JP Tokyo
- Assignee: The University of Tokyo
- Current Assignee: The University of Tokyo
- Current Assignee Address: JP Tokyo
- Agency: Morgan, Lewis & Bockius LLP
- Priority: JP2009-213645 20090915
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C12N5/02 ; C12N5/071 ; C12N5/078 ; A61K35/00
Abstract:
The present invention has an object of providing a method for producing specific cells by amplifying cells in a desired differentiation stage. The present invention provides a method for producing specific cells by inducing differentiation of cells, wherein an oncogene is forcibly expressed in cells in a desired differentiation stage to amplify the cells in the desired differentiation stage. The present invention also provides a method for producing specific cells, wherein oncogene-induced senescence (OIS) which is induced by the oncogene expressed in the cells in the desired differentiation stage is suppressed.
Public/Granted literature
- US20160115449A1 Novel Method for Producing Differentiated Cells Public/Granted day:2016-04-28
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