Invention Grant
- Patent Title: Modifications for antisense compounds
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Application No.: US15360382Application Date: 2016-11-23
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Publication No.: US10087445B2Publication Date: 2018-10-02
- Inventor: Mark Aaron Behlke , Richard Owczarzy , Yong You , Joseph Alan Walder , Kim Lennox
- Applicant: Integrated DNA Technologies, Inc.
- Applicant Address: US IA Coralville
- Assignee: Integrated DNA Technologies, Inc.
- Current Assignee: Integrated DNA Technologies, Inc.
- Current Assignee Address: US IA Coralville
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- Main IPC: C12N15/35
- IPC: C12N15/35 ; G01N33/58 ; C12N15/113 ; C12N15/11 ; C12Q1/6876
Abstract:
The invention pertains to modifications for antisense oligonucleotides, wherein the modifications are used to improve stability and provide protection from nuclease degradation. The modifications could also be incorporated into double-stranded nucleic acids, such as synthetic siRNAs and miRNAs.
Public/Granted literature
- US20170204412A1 Modifications for Antisense Compounds Public/Granted day:2017-07-20
Information query
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