A sealing arrangement includes a first and a second machine part movable relative to each other along a motional axis. A sealing element is arranged in a press fit in a plurality of grooves of a seal-holding structure of the first machine part. A sealing lip of the sealing element extends away from the seal-holding structure in the axial direction. A pretensioning element is disposed in a retaining groove of the first machine part. The sealing lip is pretensioned against a sealing surface of the second machine part in order to seal off a high-pressure region. The retaining groove has a wedge guide surface for the pretensioning element, which wedge guide surface is arranged running obliquely at an angle α, where α