A method for the determination of pollutants and leachables in a dialysis solution by stir bar sorptive extraction involves conditioning a sorptive material-coated stir bar, stirring the dialysis solution with the conditioned stir bar, desorbing of pollutants and leachables from the coated stir bar, and analyzing the desorbed pollutants and leachables by gas chromatography-mass spectrometry (GC-MS).