A LED driving system has an energy storage component receiving an input voltage, a power switch coupled between the energy storage component and a reference ground, a first output switch coupled between the energy storage component and a first output terminal, a second output switch coupled between the energy storage component and a second output terminal, and a control circuit, wherein the first output terminal produces a first output voltage to supply power for a first LED array, the second output terminal produces a second output voltage to supply power for a second LED array, the control circuit controls a duty cycle of the first output switch according to voltages at cathode terminals of multiple LED strings in the LED array and controls a duty cycle of the second output switch according to voltages at cathode terminals of multiple LED strings in the second LED array.