Invention Grant
- Patent Title: Compositions and methods of making brittle-matrix particles through blister pack freezing
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Application No.: US12778795Application Date: 2010-05-12
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Publication No.: US10092512B2Publication Date: 2018-10-09
- Inventor: Keith P. Johnston , Joshua Engstrom , Jasmine Rowe , Alan B. Watts , Robert O. Williams, III
- Applicant: Keith P. Johnston , Joshua Engstrom , Jasmine Rowe , Alan B. Watts , Robert O. Williams, III
- Applicant Address: US TX Austin
- Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Current Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
- Current Assignee Address: US TX Austin
- Agency: Parker Highlander PLLC
- Main IPC: A61K9/00
- IPC: A61K9/00
Abstract:
The present invention includes compositions and methods for treating and delivering medicinal formulations using an inhaler. The composition includes a space filled flocculated suspension having one or more flocculated particles of one or more active agents and a hydrofluoroalkane propellant. A portion of the one or more flocculated particles is templated by the formation of hydrofluoroalkane droplets upon atomization and the templated floc compacts upon the evaporation of the hydrofluoroalkane propellant to form a porous particle for deep lung delivery.
Public/Granted literature
- US20100221343A1 COMPOSITIONS AND METHODS OF MAKING BRITTLE-MATRIX PARTICLES THROUGH BLISTER PACK FREEZING Public/Granted day:2010-09-02
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