Invention Grant
- Patent Title: Salts and solid form of a BTK inhibitor
-
Application No.: US15120293Application Date: 2015-02-20
-
Publication No.: US10092569B2Publication Date: 2018-10-09
- Inventor: Mohammad Reza Masjedizadeh , Steven Gourlay
- Applicant: PRINCIPIA BIOPHARMA INC.
- Applicant Address: US CA South San Francisco
- Assignee: PRINCIPIA BIOPHARMA INC.
- Current Assignee: PRINCIPIA BIOPHARMA INC.
- Current Assignee Address: US CA South San Francisco
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- International Application: PCT/US2015/016963 WO 20150220
- International Announcement: WO2015/127310 WO 20150827
- Main IPC: A01N43/90
- IPC: A01N43/90 ; A61K31/519 ; A61K31/5395 ; A61K45/06 ; C07D487/04

Abstract:
Disclosed herein are processes for preparing 2-[(3R)-3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile free base (compound (I)), salts of compound (I) and solid state form of said salts. Also disclosed herein are pharmaceutical compositions comprising such salts and solid state form thereof and methods of treating cancer, autoimmune, and inflammatory diseases using compound (I) or a pharmaceutically acceptable salt thereof.
Public/Granted literature
- US20170065591A1 SALTS AND SOLID FORM OF A BTK INHIBITOR Public/Granted day:2017-03-09
Information query
IPC分类: