Invention Grant
- Patent Title: Gold(I) complexes with anticancer properties and methods of use thereof
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Application No.: US15586333Application Date: 2017-05-04
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Publication No.: US10092579B2Publication Date: 2018-10-09
- Inventor: Muhammad Altaf , Muhammad Monim-Ul-Mehboob , Anvarhusein Abdulkadir Isab , Saleh Altuwaijri
- Applicant: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS
- Applicant Address: SA Dhahran
- Assignee: King Fahd University of Petroleum and Minerals
- Current Assignee: King Fahd University of Petroleum and Minerals
- Current Assignee Address: SA Dhahran
- Agency: Oblon, McClelland, Maier & Neustadt, L.L.P.
- Main IPC: A61K31/66
- IPC: A61K31/66 ; A61K31/404 ; A61K31/506 ; A61K31/517 ; A61K31/44 ; A61K33/24 ; A61K39/395 ; C07F1/12 ; C07F9/50
Abstract:
Monomeric and dimeric gold(I) complexes as anticancer agents. The gold(I) complexes are coordinated to mixed ligands: one phosphine-based ligand that may be monodentate or bidentate and at least one dithiocarbamate-based ligand that is monodentate. Pharmaceutical compositions incorporating the gold(I) complexes, methods of synthesis, methods of treating cancer and methods of inhibiting cancer cell proliferation and inducing cancer cell apoptosis are also provided.
Public/Granted literature
- US20170232012A1 GOLD(I) COMPLEXES WITH ANTICANCER PROPERTIES AND METHODS OF USE THEREOF Public/Granted day:2017-08-17
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