Invention Grant
- Patent Title: High-content fast dissolving film with masking of bitter taste comprising sildenafil as active ingredient
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Application No.: US14379989Application Date: 2013-02-28
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Publication No.: US10092651B2Publication Date: 2018-10-09
- Inventor: Hyun Jun Jeong , Ik Hyeon Chang , Dal Geun Kim , Jin Hoo Lee , Jin Hee Um , Hyun Soo Kim , Kyung Tae Jung , Kyu Jeong Yeon , Jin Gyu Park
- Applicant: SEOUL PHARMA CO., LTD.
- Applicant Address: KR Gyeonggi-do
- Assignee: SEOUL PHARMA CO., LTD.
- Current Assignee: SEOUL PHARMA CO., LTD.
- Current Assignee Address: KR Gyeonggi-do
- Agency: Harness, Dickey & Pierce, P.L.C.
- Priority: KR10-2012-0020316 20120228; KR10-2012-0117233 20121022
- International Application: PCT/KR2013/001679 WO 20130228
- International Announcement: WO2013/129889 WO 20130906
- Main IPC: A61K47/02
- IPC: A61K47/02 ; A61K31/519 ; A61K47/10 ; A61K47/26 ; A61K47/36 ; A61K9/00 ; A61K9/70

Abstract:
Provided is a fast dissolving film composition comprising a medically active component as an active ingredient, in which the bitter taste of the active ingredient is masked and the fast dissolving film composition has a high content of 50% or higher. More particularly, provided is a pharmaceutical composition which comprises sildenafil or pharmaceutically acceptable salts thereof as an active ingredient, and which comprises a combination of a specific bitter taste masking agent to achieve masking of a bitter taste. Further, provided is a fast dissolving film composition which comprises a combination of a specific plasticizer to mask a bitter taste, and in which the physical properties of the high-content film are excellent.
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