Invention Grant
- Patent Title: Cyclic amides as MetAP-2 inhibitors
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Application No.: US14390926Application Date: 2013-03-21
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Publication No.: US10093623B2Publication Date: 2018-10-09
- Inventor: Timo Heinrich , Frank Zenke , Mireille Krier , Manja Friese-Hamim , Jeyaprakashnarayanan Seenisamy
- Applicant: MERCK PATENT GmbH
- Applicant Address: DE Darmstadt
- Assignee: MERCK PATENT GmbH
- Current Assignee: MERCK PATENT GmbH
- Current Assignee Address: DE Darmstadt
- Agency: Millen White Zelano and Branigan, PC
- Agent John Sopp
- Priority: DE102012006884 20120404
- International Application: PCT/EP2013/000867 WO 20130321
- International Announcement: WO2013/149704 WO 20131010
- Main IPC: A61K31/40
- IPC: A61K31/40 ; A61K31/402 ; A61K31/4035 ; A61K31/4184 ; A61K31/445 ; A61K31/45 ; A61K31/451 ; A61K31/541 ; A61K31/55 ; A61K45/06 ; C07D207/12 ; C07D207/16 ; C07D207/24 ; C07D207/26 ; C07D207/267 ; C07D207/277 ; C07D211/60 ; C07D211/74 ; C07D211/76 ; C07D211/78 ; C07D223/08 ; C07D401/04 ; C07D401/06 ; C07D401/10 ; C07D403/04 ; C07D403/06 ; C07D403/10 ; C07D403/14 ; C07D417/06 ; C07D223/10
Abstract:
Described are cyclic amide compounds of the formula (I): in which R1, R3, R5, R6, R7, R, X and Y have the meanings as described. The compounds are inhibitors of methionine aminopeptidase and can be employed for the treatment of tumors.
Public/Granted literature
- US20150031670A1 CYCLIC AMIDES AS METAP-2 INHIBITORS Public/Granted day:2015-01-29
Information query
