- Patent Title: Tetrahydroquinoline derivatives and their use as Epac inhibitors
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Application No.: US15661143Application Date: 2017-07-27
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Publication No.: US10093627B2Publication Date: 2018-10-09
- Inventor: Frank Lezoualc'h , Rodolphe Fischmeister , Malik Bisserier , Pascal Bouyssou , Jean-Paul Blondeau , Delphine Courilleau
- Applicant: Institut National de la Sante et de la Recherche Medicale (INSERM) , Universite Paul Sabatier Toulouse III , Universite Paris-Sud , Universite d'Orleans
- Applicant Address: FR Paris FR Toulouse FR Orsay FR Orleans
- Assignee: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM),UNIVERSITE PAUL SABATIER TOULOUSE III,UNIVERSITE PARIS-SUD,UNIVERSITE D'ORLEANS
- Current Assignee: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM),UNIVERSITE PAUL SABATIER TOULOUSE III,UNIVERSITE PARIS-SUD,UNIVERSITE D'ORLEANS
- Current Assignee Address: FR Paris FR Toulouse FR Orsay FR Orleans
- Agency: W&C IP
- Priority: EP12306201 20121002
- Main IPC: A01N57/00
- IPC: A01N57/00 ; A61K31/66 ; C07D215/14 ; A61K31/47 ; C07D215/08 ; C07D215/18
Abstract:
The invention relates to tetrahydroquinoline derivatives and their use in the treatment and/or the prevention of a disease wherein the Epac protein is involved, such as inflammation, cancer, vascular diseases, kidney diseases, cognitive disorders and cardiac diseases.
Public/Granted literature
- US20180009757A1 Tetrahydroquinoline Derivatives and Their Use as Epac Inhibitors Public/Granted day:2018-01-11
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