Invention Grant
- Patent Title: Compositions and methods for brown fat induction and activity using FNDC5
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Application No.: US14344460Application Date: 2012-09-12
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Publication No.: US10093705B2Publication Date: 2018-10-09
- Inventor: Bruce M. Spiegelman , Pontus Bostrom
- Applicant: Bruce M. Spiegelman , Pontus Bostrom
- Applicant Address: US MA Boston
- Assignee: Dana-Farber Cancer Institute, Inc.
- Current Assignee: Dana-Farber Cancer Institute, Inc.
- Current Assignee Address: US MA Boston
- Agency: Foley Hoag LLP
- International Application: PCT/US2012/054797 WO 20120912
- International Announcement: WO2013/039996 WO 20130321
- Main IPC: C07K14/47
- IPC: C07K14/47 ; C07K14/78 ; C07K19/00 ; C07K14/435 ; C07K16/18 ; C07K14/575 ; A61K38/00
Abstract:
The invention provides compositions and methods for brown fat induction and activity through modulation of Fndc5 activity and/or expression. Also provided are methods for preventing or treating metabolic disorders in a subject through modulation of Fndc5 activity and/or expression. Further provided are methods for identifying compounds that are capable of modulating Fndc5 activity and/or expression.
Public/Granted literature
- US20150203549A1 COMPOSITIONS AND METHODS FOR BROWN FAT INDUCTION AND ACTIVITY USING FNDC5 Public/Granted day:2015-07-23
Information query
