Invention Grant
- Patent Title: Anti-NGF antibodies and their use
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Application No.: US14799182Application Date: 2015-07-14
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Publication No.: US10093725B2Publication Date: 2018-10-09
- Inventor: Susan E. Lacy , Jeffrey A. Barbon , Meha Chhaya , Emma Fung , Charles W. Hutchins , Diane M. Lang , Eve H. Barlow , Mary Leddy , Ravi Chari
- Applicant: Zoetis Belgium S.A.
- Applicant Address: BE Louvain-la-Neuve
- Assignee: ZOETIS BELGIUM S.A.
- Current Assignee: ZOETIS BELGIUM S.A.
- Current Assignee Address: BE Louvain-la-Neuve
- Agent Kelly M. Sullivan
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/22 ; G01N33/566 ; A61K39/00

Abstract:
The present disclosure encompasses NGF binding proteins, specifically to antibodies that are chimeric, CDR grafted and canonized antibodies, and methods of making and uses thereof. The antibodies, or antibody portions, of the disclosure are useful for detecting NGF and for inhibiting NGF activity, e.g., in a mammal subject suffering from a disorder in which NGF activity is detrimental.
Public/Granted literature
- US20160264656A1 ANTI-NGF ANTIBODIES AND THEIR USE Public/Granted day:2016-09-15
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