• Patent Title: Compositions and methods for creating altered and improved cells and organisms
  • Application No.: US14653840
    Application Date: 2013-12-19
  • Publication No.: US10093922B2
    Publication Date: 2018-10-09
  • Inventor: Helge Zieler
  • Applicant: Helge Zieler
  • Agency: Gorman IP Law, APC
  • International Application: PCT/US2013/076526 WO 20131219
  • International Announcement: WO2014/100400 WO 20140626
  • Main IPC: C12N15/10
  • IPC: C12N15/10 C12N15/81 C12N15/70 C07H21/02
Compositions and methods for creating altered and improved cells and organisms
Abstract:
The present invention provides compositions comprising randomized in-frame fusion polynucleotides and methods for introducing them into a host organism to identify desirable phenotypic changes that disrupt or alter existing genetic or biochemical mechanisms or pathways, thus creating novel characteristics of the transformed organism. Methods for using the compositions for increasing diversity within populations of organisms are also presented.
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