Invention Grant
- Patent Title: Reduction of off-target RNA interference toxicity
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Application No.: US15482284Application Date: 2017-04-07
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Publication No.: US10093927B2Publication Date: 2018-10-09
- Inventor: Beverly L. Davidson , Alejandro Mas Monteys , Jodi McBride , Ryan Boudreau
- Applicant: UNIVERSITY OF IOWA RESEARCH FOUNDATION
- Applicant Address: US IA Iowa City
- Assignee: University of Iowa Research Foundation
- Current Assignee: University of Iowa Research Foundation
- Current Assignee Address: US IA Iowa City
- Agency: Viksnins Harris Padys Malen LLP
- Main IPC: A61K48/00
- IPC: A61K48/00 ; C07H21/02 ; C07H21/04 ; C12N15/113 ; C12N15/11
Abstract:
The present invention is directed to RNA interference (RNAi) molecules targeted against a nucleic acid sequence, and methods of using these RNAi molecules to reduce off-target toxicity.
Public/Granted literature
- US20170369877A1 REDUCTION OF OFF-TARGET RNA INTERFERENCE TOXICITY Public/Granted day:2017-12-28
Information query
